Biphenyl-substituted antibacterial macrocycles

Antibakterielle makrozyklen mit substituiertem biphenyl

Macrocycles antibacteriens a substitution biphenyle

Abstract

The invention relates to biphenyl-substituted antibacterial macrocycles, to methods for their production, to their use in the treatment and/or prophylaxis of diseases, in addition to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infections.
Die Erfindung betrifft antibakterielle Makrozyklen mit substituiertem Biphenyl und Verfahren zu ihrer Herstellung, ihre Verwendung zur Behandlung und/oder Prophylaxe von Krankheiten sowie ihre Verwendung zur Herstellung von Arzneimitteln zur Behandlung und/oder Prophylaxe von Krankheiten, insbesondere von bakteriellen Infektionen.
L'invention concerne des macrocycles antibactériens à substitution biphényle, des procédés de production de ces macrocycles antibactériens, leur utilisation pour traiter et/ou prévenir des maladies, ainsi que leur utilisation pour produire des médicaments servant à traiter et/ou prévenir des maladies, en particulier des infections bactériennes.

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Patent Citations (1)

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NO-Patent Citations (5)

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    EP-2386547-A1November 16, 2011Lexicon Pharmaceuticals, Inc.Multicyclic amino acid derivatives and methods of their use
    US-7655643-B2February 02, 2010Aicuris Gmbh & Co. KgAntibacterial macrocycles with substituted biphenyl
    WO-2006103015-A1October 05, 2006Aicuris Gmbh & Co. KgAntibacterial amide-macrocycles v
    WO-2007006548-A2January 18, 2007Aicuris Gmbh & Co. KgAntibacterial amide macrocycles vii
    WO-2007006548-A3March 22, 2007Aicuris Gmbh & Co Kg, Rainer Endermann, Kerstin Ehlert, Martin Michels, Stefan Weigand, Guido SchifferMacrocycles d'amide vii antibacteriens